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The Entourage Effect May Help Improve Health

“There is not enough research!” That is the cry heard around the country as medical marijuana proliferates the states. This is not about the long-running TV show centered on young actors trying to make it big in Hollywood, but the effect of the whole cannabis plant on our health. It’s called the “entourage effect” –a slick name for a simple concept: the whole is greater than the sum of its parts. You may know this as synergy.

When we consume cannabis, we’re ingesting a collection of cannabinoids, terpenes, and flavonoids, making up the group of ingredients sort of like an entourage that follows a celebrity. In the medical cannabis world, the “entourage effect” is widely advocated but narrowly–if at all–formally studied in research projects. That’s why it’s creating buzz in the industry and among our patients.

Many are touting their success by using a broad-spectrum or full-spectrum therapy.

They Work Together

As a patient, you are most likely aware of the two most famous compounds, THC and CBD. Organic Remedies Pharmacist Shannon Ye says, “I start off with the two primary cannabinoids, THC and CBD, and describe their properties and potential synergistic effect.” Then, Ye moves into a deeper realm by discussing strains.  “Afterwards, I explain the general differences between sativa, hybrid, and indica strains.”

Starting with strains is just the beginning of delving into the entourage effect of cannabis. Ye’s interest in the effect is helping patients make their way through what can be a daunting first experience and lead to a better overall cannabis therapy. Ye discusses hybrids then moves to terpenes saying, “I explain that cross-breeding over the years has led to many hybrid strains, and that the terpenes, the natural oils that provide aroma and medicinal value, greatly help to distinguish the potential effects and benefits.”

New Approach

This will be new territory for many first-time medical marijuana patients and going slow with the explanation goes well with the dosing mantra of “start low, go slow.”

Ye walks her patients through a major difference in their new medical therapy. We are working with a natural plant, not a synthetic compound developed in a lab. “With many patients only familiar with single compound synthetic pharmaceuticals and new to plant-based medicine, I distinguish cannabis as the ultimate combination medication.” Ye expands on that crucial difference between medical marijuana and synthetic meds. “Ultimately, I express that the benefits of cannabis do not rely on one component.  Rather, there may be a synergy when cannabinoids and terpenes are combined to deliver an enhanced pharmacologic effect.”

How Important is “Anecdotal” Evidence?

Ye agrees more research will help with defining and applying the entourage effect, but in the meantime, she’s seeing more patients benefitting from it. “I have observed from our patients that oftentimes the products containing a more abundant cannabinoid and terpene profile seem to offer greater benefits.”

Ye says the effects of cannabis are highly individualized. So too, are the effects of different products available at Organic Remedies. Ye says, “Many of our Organic Remedies’ extracted products are full spectrum concentrates because the specific cannabinoid and terpene profile of the plant is preserved during the manufacturing process.

Ye says patients can help a pharmacist dial-in a perfect entourage. “For example, one of my patients was having difficulty finding a capsule to help with sleep,” Ye says. “After a distillate 10 mg THC capsule was not effective, trying an indica-dominant full spectrum RSO 10 mg THC capsule finally provided the patient a good night's rest.”

Check Out the Terpenes!

Because of the entourage effect, patients may find that trying products with a different terpene profile creates a very different experience and can improve individual outcomes Ye relies on our lab’s work in extraction and production. “With patients, I often click on the product on our menu to look at the terpene contents obtained from the lab. Our Grape Cake dry leaf is an indica THC-dominant strain that is high in myrcene, a terpene that provides sedative effects.

Fortunately for patients, with the increasing number of strains, the various terpenes and new product forms coming to market, the benefits of the entourage effect can seem endless. “Our AK live crumble was created via an extraction process where the plant is fresh-frozen. It’s abundant in several terpenes. Also, check out strain-specific full spectrum tinctures which often provide a fuller "entourage" effect than our flavored tinctures.”

Research on the entourage effect includes the work of Dr. Ethan B. Russo. You can find his January 2019 study here: The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain (nih.gov)

An Organic Remedies Patient Care Consultant and Pharmacist are always available to answer your questions!

The Entourage Effect Overview horizontal business infographic illustration about cannabis as herbal alternative medicine and chemical therapy, healthcare and medical science vector.

Organic Remedies Career Fair

Join us at our Career Fair to learn about how you can join our team!

July 28, 2021

3 p.m. - 6:30 p.m.

We are hiring for full-time positions at our cultivation and manufacturing facility.

  • INVENTORY CONTROL SPECIALISTS
  • CULTIVATORS
  • PROCESSORS
  • PACKAGERS
  • SHIPPERS
  • SECURITY GUARDS
  • PORTERS
  • MAINTENANCE TECHNICIANS
Hiring managers will be onsite
Apply in person
Competitive wages
Great working environment
Health & Retirement Benefits
Organic Remedies Medical Marijuana Dispensary
Must be able to work weekends and various shifts
Must have reliable transportation
MUST be able to pass a federal and state criminal background check

Two is Often Better Than One

One thing you can always count on in the medical marijuana field is change. We are in a time of incredible advancement, development and innovative therapies involving cannabis. When perusing medical marijuana menus, you may come across a 1:1 product. This is usually a half and half combination of CBD (cannabidiol) and THC (tetrahydrocannabinol).

The THC Component is Important

Combining THC with CBD is showing promising results. The University of Western Ontario showed in 2019 for the first time the molecular mechanisms of CBD at work, block the psychoactive side-effects of THC. Uncovering those “molecular mechanisms” in mice, allowed the team to isolate the reaction of those given a CBD/THC combination. They presented fewer anxiety behaviors and other negative side effects.

The National Institutes of Health reports the 1:1 combination of THC:CBD appears to allow for higher doses of THC without increasing the risk of adverse side effects. It appears that CBD acts to antagonize some of the psychoactive and sedative effects of THC without interfering with intended THC effects, such as muscle relaxation and reduction of spasticity.

I Don’t Want to get High, So Why the THC?

Organic Remedies Pharmacist Tammy Royer says, “THC helps CBD bind to the receptors resulting in increased effectiveness of the CBD, while CBD lowers some of the euphoric effects of THC, without losing the value of THC. A one-to-one ratio has minimal euphoric effects, but can be very helpful for symptom relief for many qualifying conditions.”

Royer also points out an easy way for patients to open discussions about their treatment. All Organic Remedies products label the amounts of THC and CBD, “The higher the percentage of CBD to THC in a product, the less euphoria or psychoactive effect will be experienced,” says Royer.

CBD is beneficial as an anti-inflammatory, for nerve pain relief, and in relieving anxiety. Royer adds, “use of even minimal amounts of THC in a CBD product will mean greater levels of attachment to receptors and more relief, especially if taken regularly to saturate the receptors.”

Some Products to Consider

Dialing in your own CBD:THC ratio and dose can have a learning curve, but Organic Remedies Patient Care Consultants and Pharmacists can help. Ultimately, the goal is finding the right ratio of CBD to THC.

Patients can start off adding 1mg of THC at a time with their normal CBD dose and slowly build up to a level that produces the best result. Organic Remedies Pharmacist Patrick Gladfelter says, “By titrating up slowly, the patient can determine an effective dose, while achieving the desired relief. At the same time, he or she can perform daily tasks with minimal unwanted side effects.”

While both compounds can help reduce symptoms, including inflammation, pain, anxiety, and nausea, the concentration of CBD:THC can affect the experience. Gladfelter says, “When choosing a product and initial dosing, in general, I base my recommendation on THC concentration to avoid unwanted side effects such as anxiety or euphoria. Then as CBD builds up during the 7to10-day loading phase, the synergy of THC and CBD really kicks in!”

Available research and anecdotal evidence show that CBD and THC are a complementary pair. Gladfelter adds, “As new information and data is collected, we are gaining a better understanding of cannabis and its many components. These two important cannabinoids not only work better together, but may also provide the same amount of relief, possibly better, with less euphoria compared to a THC product alone.”

Organic Remedies can help you find the right product and ratio depending on your preference.

A beautiful sheet of cannabis marijuana in the defocus with the image of the formula CBD

Post-traumatic Stress Disorder and Cannabis

A shocking, scary, or dangerous event can cause the body to develop post-traumatic stress disorder (PTSD). It is natural to feel fear during and immediately after a traumatic situation. Split second decisions are made in the “fight or flight” response. But, when a person does not recover naturally from a trauma, the long-term effects can be devastating.

Step One: Talk to your Organic Remedies Pharmacist

If you have been diagnosed with PTSD and are considering medical marijuana therapy, Organic Remedies Pharmacist Shannon Ye says, “Information gathered from non-professional sources may not always provide the best results. Treatments can greatly differ among patients. Efficacy is closely tied to finding the appropriate dose and strains.”

While the most studied type of medications for treating PTSD are antidepressants, which may help control symptoms including sadness, worry, anger, and feeling numb inside, medical cannabis may also be helpful in alleviating many different symptoms as well. Other common problems associated with PTSD, that may be helped by medical cannabis, include loss of sleep and nightmares.

Right now, the National Institute of Mental Health says medical professionals and patients should work together to find the best medication or medication combination, as well as the right dose. Ye agrees that this is important with medical cannabis as well, saying, “For example, a dose too high in THC and pinene may worsen PTSD related symptoms therefore agitating anxiety and irritability. Having a traumatic experience from cannabis may not only worsen PTSD symptoms but may also prevent a patient from trying cannabis again in the future.”

Individualized Therapy

The NIMH also recommends psychotherapy, or “talk therapy,” for people with PTSD, but stresses every patient is different. What works for one, often does not work for another. “I always ask the patient about their goals of therapy and what dosage forms they may feel most comfortable using,” says Ye.  “Although more research is needed, there is evidence that supports cannabis alleviates difficult to treat symptoms of PTSD such as insomnia, nightmares, anxiety, and irritability. There is also evidence that cannabis can help a PTSD patient experience a "trigger" without an associated terror response.”

Not having that terror response to a particular “trigger” is key in treatment. Ye says, “The success in treating symptoms may be due to PTSD patients having changes in their endocannabinoid system. However, it is not realistic for patients to expect medical cannabis to cure their PTSD as it is not a substitute for conventional treatment.”

PTSD is Personal

PTSD diagnosis is based on many factors including re-experiencing symptoms, avoiding certain things, and changes in mood and cognition. With so many things to consider, both patient and pharmacist can work together to find a way to improve the quality of life.

Ye says every case is one-of-a-kind, “As an example, one of my recent patients I spoke to was suffering PTSD due to a car accident from 2 years ago. Ye says the symptoms were paralyzing, “They were experiencing anger that led to blackouts and anxiety that caused panic attacks when in a car. They have noticed significant improvement in managing PTSD symptoms since starting cannabis.”

Finding the Right Combo

Ye says finding a particular strain for PTSD patients is important but when she digs deeper into therapy, Ye finds hope in the terpenes. “It may be best to avoid strains high in pinene, as the alerting effects may be anxiety-provoking and memory-enhancing to past trauma. However, strains higher in linalool may be anxiolytic and calming.

With an Organic Remedies’ Pharmacist guidance, quality of life reports continue to improve with the help of cannabis. Ye’s patient from the car accident is getting results from a higher CBD strain during the day. “Any 1:1 (CBD/THC) may be a suitable option, especially during the day. Limonene is an uplifting, antidepressant terpene that may be preferable during the day as well.”

With quality of sleep ranking high in PTSD patients another treatment may help at night. Ye says, “higher THC indica-dominant "Kush" and "Purple" strains may be effective towards the evening in treating sleep disturbances.”

An Organic Remedies pharmacist is always available to answer questions.

RESOURCES

From National Institute of Mental Health

Some factors that increase risk for PTSD include:

  • Living through dangerous events and traumas
  • Getting hurt
  • Seeing another person hurt, or seeing a dead body
  • Childhood trauma
  • Feeling horror, helplessness, or extreme fear
  • Having little or no social support after the event
  • Dealing with extra stress after the event, such as loss of a loved one, pain and injury, or loss of a job or home
  • Having a history of mental illness or substance abuse

Some factors that may promote recovery after trauma include:

  • Seeking out support from other people, such as friends and family
  • Finding a support group after a traumatic event
  • Learning to feel good about one’s own actions in the face of danger
  • Having a positive coping strategy, or a way of getting through the bad event and learning from it
  • Being able to act and respond effectively despite feeling fear

Learn More

https://www.nimh.nih.gov/health/publications/helping-children-and-adolescents-cope-with-disasters-and-other-traumatic-events/

https://www.nimh.nih.gov/health/publications/post-traumatic-stress-disorder-ptsd/

https://www.nimh.nih.gov/get-involved/education-awareness/shareable-resources-on-ptsd

https://www.ptsd.va.gov/index.asp

https://www.ptsd.va.gov/professional/treat/txessentials/clinician_guide_meds.asp

https://medlineplus.gov/posttraumaticstressdisorder.html

Head shape with PTSD Post traumatic stress disorder.

710! Downright Upside Down!

On the heels of the July 4th holiday weekend, we are headed into a big weekend in the cannabis industry. July 10th, known as 710, is National Dab Day. Cannabis concentrate lovers around the globe celebrate July 10. The day now includes the celebration of all cannabis concentrate forms. During extraction, organic plant matter is separated from the plant’s resin containing cannabinoids, terpenes, and flavonoids.

Here are some forms of cannabis concentrates:

  • Shatter
  • Wax
  • Crumble
  • Budder
  • Live Resin
  • Terp Sauce
  • Diamonds
  • Hash
  • Distillate
  • Oil
  • Isolate
  • Rosin

Organic Remedies is also adding a new dab called “sap.” Our Sap syringes are a combination of distillate and high terpene extract (HTE) oils, giving you the best of both worlds in THC and terpene content. It is fully activated and may be ingested or vaporized.

No matter what form you enjoy, 710 gives a nod to all cannabis concentrate forms.

710 is World-wide 

According to market research and consulting company,  Grand View Research, the global marijuana extract market size was valued at $7.3 billion in 2019. Grand View says there is no sign of slowing down. Growing medical and recreational markets around the world have increased the global presence and popularity of cannabis concentrates.

Why July 10?

710 has become a worldwide phenomenon due to legal cannabis markets’ introduction of cannabis concentrates to consumers. So, now under “concentrates,” we see a range from THC-potent wax to CBD-rich tincture that can be consumed orally or sublingually.

710 is now the unofficial designation for cannabis extracts solely because when you flip the 710 date upside down, it spells oil. (See the video!)

What is 710 Day?

Naturally, 710 Day turned into a special day to honor the resinous oil that comes from the cannabis plant. Every year, July 10th (7/10) is an international holiday for cannabis enthusiasts. People all over celebrate by vaporizing a wide selection of concentrates, and even the use of transdermal patches and creams fall under the “7/10” celebration.

It’s all in the number(s)

Like many things in the cannabis industry, the history of national oil day (7/10) is a mystery. 710 really took off with the legalization of cannabis in early-adopting states. As medical and recreational programs became popular, patients and grower/processors began to realize the benefits of a concentrated form of cannabis – or 710 in cannabis-speak.

710 became a mainstay in the cannabis community with the introduction of the 710 Cup in 2012, which takes place on the 10th of July. The event recognizes the best products in a number of categories including Distillate, Concentrate Sativa/Indica/Hybrid, CBD Concentrate, and more categories.

Since then, 710 has become an easy way to talk about dabs and dabbing, in general. 7/10 may not be as culturally significant as 4/20, but it is a great holiday to enjoy alone or with friends.

Do Not Confuse the Numbers!

By now, most cannabis patients and rec users know about 420. It refers to the decades-old marijuana holiday that occurs on April 20 (4/20). Cannabis users around the world gather to celebrate the psychedelic plant. 420 began in the early 70’s in California. A group of San Rafael High School students who referred to themselves as “The Waldos.” would meet up at 4:20 pm after school to search for a rumored weed stash on school grounds. It turns out, one of the Waldos, Dave Reddix, got a gig as a roadie for the Grateful Dead where the term started picking up steam. Eventually, the band produced flyers to invite fans to join them for some good tunes and smoke at, yes, 4:20 PM.

Happy 710 Day

7/10 events span far and wide in legal states such as Colorado, California, Oregon, and Washington. Check out your nearest dispensary and favorite cannabis business for steep discounts on product and gear. If you love Piña Coladas, you can also celebrate National Piña Colada Day on July 10th. Love cats and kittens? 7/10 is also National Kitten Day.

If you have any questions about concentrates, don’t think you have to ask on 710! Our Organic Remedies pharmacists are always available to answer your questions.

710

Medical Marijuana May Be Beneficial in Managing Alzheimer’s Disease

June is Alzheimer’s and Brain Awareness Month so we turn our spotlight on this insidious disease and how medical cannabis may help. While there is a wealth of information about Alzheimer’s Disease, treating it, living with a loved one coping with it, and helping those afflicted are continuing challenges. The Centers for Disease Control and Prevention is teaming up with the Alzheimer’s Association in the Healthy Brain Initiative. The American Association of Retired People also offers a free “Staying Sharp Brain Health Assessment” in June.

Warning Signs

Common signs of AD are often first noticed by the person affected. Memory changes as we age, but certain types of memory loss are not typical. The CDC offers these guidelines for early assessment. People with one or more of these 10 warning signs should see a doctor to find the cause. Early diagnosis gives them a chance to seek treatment and plan.

·        Memory loss that disrupts daily life: forgetting events, repeating yourself or relying on more aids to help you remember (like sticky notes or reminders).

·        Challenges in planning or solving problems: having trouble paying bills or cooking recipes you have used for years.

·        Difficulty completing familiar tasks at home, at work, or at leisure: having problems with cooking, driving places, using a cell phone, or shopping.

·        Confusion with time or place: having trouble understanding an event that is happening later or losing track of dates.

·        Trouble understanding visual images and spatial relations: having more difficulty with balance or judging distance, tripping over things at home, or spilling or dropping things more often.

·        New problems with words in speaking or writing: having trouble following or joining a conversation or struggling to find a word you are looking for (saying “that thing on your wrist that tells time” instead of “watch”).

·        Misplacing things and losing the ability to retrace steps: placing car keys in the washer or dryer or not being able to retrace steps to find something.

·        Decreased or poor judgment: being a victim of a scam, not managing money well, paying less attention to hygiene, or having trouble taking care of a pet.

·        Withdrawal from work or social activities: not wanting to go to church or other activities as you usually do, not being able to follow football games or keep up with what’s happening.

·        Changes in mood and personality: getting easily upset in common situations or being fearful or suspicious.

We turn to Organic Remedies’ Pharmacist, Nick Signorella for answers to how therapy with medical cannabis may help. “A lot of our treatment with Alzheimer’s has to do with symptom management. Specifically, marijuana can help with food intake, agitation, sleep, and overall mood.” Signorella adds, “THC can help to increase food intake, help with agitation at lower doses, improve sleep, and improve mood/depression at lower doses.”

AD symptoms that may respond to cannabis include, sleep problems, paranoia, anxiety, dysphoria, pain, poor appetite, and weight loss. Signorella says AD patients may live a better lifestyle by examining a medical marijuana therapy. “For example, THC can inhibit acetylcholinesterase through the CB1 receptor, which theoretically could help to minimize the decline in cognitive function.” Signorella goes deeper, “Additionally CB2 receptor levels are increased in Alzheimer’s patients. The anti-inflammatory effects from CBD activating the CBD2 receptor could help reduce inflammation and neurotoxicity associated with Alzheimer’s.”

Dosage

Signorella would advise AD patients to turn to the many newly created cannabis delivery options including tinctures and capsules. But, he says, “caution should be used with higher doses of THC as this can actually cause increased agitation and disorientation. In general, the starting dosage for agitation and sleep should be around 2.5-5mg of THC depending on experience. CBD on the other hand can help with agitation, typically at lower doses, usually starting around 5mg of CBD.”  He adds, “I would typically start with a 1:1 ratio of THC:CBD, around 2.5mg or 5mg of each. It would depend on the specific patient, but generally lower to moderate doses of both THC and CBD would be used.”

Searching for Answers

Evidence is not as robust for the treatment of Alzheimer’s, but there is some anecdotal evidence cannabis can be beneficial. Many of the mechanisms in the prescription drug donepezil, commonly used to treat AD, are similar. Signorella says, “overall cannabis can help to improve quality of life for both the patient and caregiver, while potentially help to manage disease progression as well.”

During this June Alzheimer’s and Brain Awareness month, remember your Organic Remedies pharmacist may be able to help!

More info: The Centers for Disease Control and Prevention (CDC) and the Alzheimer’s Association have created the Healthy Brain Initiative’s (HBI) State and Local Public Health Partnerships to Address Dementia: The 2018-2023 Road Map.

 

Senior with Alzheimer's or dementia has difficulty with puzzle pieces.

Parkinson’s Research Shows Promise in Medical Marijuana Therapy

We’re always excited to provide new information on research into the medical use of cannabis. Now, there’s news on research into Parkinson’s disease and medical marijuana. Parkinson’s is a neurodegenerative brain disorder. Patients face the worst prognosis: there is no known cure for this debilitating disease. But, there is hope. The latest news from the Parkinson’s Foundation shows cannabis as a new treatment option. The Parkinson's Foundation announced the results of its medical cannabis and Parkinson's disease (PD) survey. The survey, Weeding Through the Haze: A Survey on Cannabis Use Among People Living with Parkinson's Disease in the U.S., was completed by 1,064 people with PD.

The survey asked specific questions about cannabis use ― from symptom management to motivation for use and side effects ― and questions for those who do not use cannabis and why. About a quarter of the respondents used cannabis within the previous six months. Less than 13 percent reported negative side effects from cannabis use. Interestingly, more than half of the respondents learned about cannabis use from the internet or from friends or other people with PD.

Organic Remedies is Helping Patients Find Answers

At Organic Remedies, we turn to our pharmacists when questions arise. PharmD Shannon Ye, from our Enola dispensary was pleased to see the new Parkinson’s Foundation study, but says: “Unfortunately, few of the patients I speak with inquire about how medical cannabis could help manage and alleviate the symptoms of Parkinson's disease.” The findings point to a different direction among Parkinson’s patients; they want to know what’s available to help them, but medical cannabis doesn’t always come to mind. “I am not surprised at this finding,” said Ye. “I can recall that the majority of initial patients I've spoken to who live with Parkinson's disease are unaware of key aspects of medical cannabis.  Many of these patients lack knowledge regarding the potential side effects and dosages of medical cannabis or may have learned from inaccurate or misleading sources.”

Parkinson’s Foundation Looking For Better Outcomes

"At a time when cannabis is legal in more states than ever before, we believe this survey provides new and critical information for the growing population of cannabis users who have Parkinson's disease," said James Beck, PhD, Senior Vice President and Chief Scientific Officer of the Parkinson's Foundation. "Ultimately, our goal is better outcomes for everyone living with Parkinson's disease and we're committed to tackling issues that are a priority for the PD community."

The survey results show that there is a knowledge gap among people living with PD, which may be impacting their decisions about cannabis use. More than half of the respondents were not provided any information on how to use cannabis such as dosage, type and frequency of use. More than 60% had not received a cannabis recommendation from a licensed doctor or provider and overall, 89 percent said cannabis was not a replacement for their PD prescription medication.

Organic Remedies’ Superior Patient Experience

Those numbers may surprise you if you are a patient of Organic Remedies. A full 60 percent did not get advice from a medical professional. We offer a superior relationship between the patient and pharmacist.

Ye says, “For new and current patients living with Parkinson's disease who have a medical marijuana certification, I highly encourage them to schedule a consultation.  As a pharmacist at Organic Remedies, my priority is in providing quality patient care and offering education and recommendations that may best accomplish my patients' treatment goals.”

Organic Remedies' Research with Philadelphia College of Osteopathic Medicine

Organic Remedies’ vision is to be a leader in the advancement of medical cannabis therapy through innovative genetic programs, patient-focused care, and clinical research to realize the full potential of marijuana to improve overall wellness.

Our mission is to improve the overall wellness of our patients by producing and dispensing affordable quality medical marijuana products while continuing the advancement of medical marijuana therapies through genetics, collaborative research, and superior patient care. Right now, our research with PCOM is well underway.

While not focused on Parkinson’s disease, the quality of life surrounding medical marijuana use is central to Organic Remedies’ scientific approach.

"As part of our research partnership with Organic Remedies, Philadelphia College of Osteopathic Medicine (PCOM) is investigating how quality of life may change in the year after patients initiate medical marijuana treatment," said Michelle Lent, PhD, associate professor of clinical psychology at PCOM. "Specifically, we are evaluating changes in their emotional, social, occupational, and physical functioning."

The Parkinson’s Foundation Conclusion

In the U.S., cannabis has become more widely available for medical and recreational use. Until now, there was insufficient data about the attitudes towards, and experiences with, cannabis use among those living with PD. This survey aims to address this disparity. The 1,064 survey respondents came from 49 states. The average age for respondents was 71, and the average time they have lived with Parkinson's is seven years.

Doctor writing word Parkinson's Disease with marker, Medical concept

ORGANIC REMEDIES’ CUTS THE RIBBON ON COMPANY’S FIRST MEDICAL MARIJUANA DISPENSARY IN MISSOURI

New Dispensary Provides Safe, Effective Therapies for Cape Girardeau Patients Suffering with Serious Medical Conditions

CAPE GIRARDEAU, Mo. (April 6, 2021)- Organic Remedies, a medical marijuana cultivation and research organization based in southcentral Pennsylvania, is celebrating the upcoming opening of its first Missouri dispensary at 350 N. Kingshighway, Cape Girardeau. Organic Remedies President Eric Hauser, RPh., along with state and local dignitaries and medical marijuana advocates, cut the ceremonial ribbon during the Open House event on Tues., April 6 at 10:00 a.m., one of several special activities planned before the dispensary officially opens for business to patients.

"We are proud to bring our unique brand of patient-focused healthcare to the city of Cape Girardeau," said Eric Hauser, RPh., President, Organic Remedies. "Since 2018, we have been strongly focused on improving the health and wellness of patients through medical marijuana therapies, and we look forward to supporting Missouri patients who are struggling with serious health conditions. We are also committed to becoming a vital member of the thriving Cape Girardeau community by offering new employment opportunities, supporting local veterans’ organizations, participating in community outreach events, and giving back to our communities through charitable contributions."

The ribbon cutting ceremony kicked off several special events planned at the Cape Girardeau dispensary, including:

  • Morning of Wed., April 7, Organic Remedies plans to host an Open House for the area’s first responders, law enforcement and emergency officials with tours of the dispensary and information about the medicinal benefits of medical marijuana.
  • Afternoon of Wed., April 7, the new dispensary will be open to the area’s healthcare providers to tour the facility and learn more about medical marijuana products and the therapeutic benefits for patients.
  • Thurs., April 8, the company is planning to host a “Meet the Cultivators/Manufacturers” community event, where the public can learn first-hand about the medical marijuana industry from many of Missouri’s own marijuana cultivators and manufacturers.

The Cape Girardeau dispensary is expected to officially open for business mid-April. New patients can visit the company’s website at www.organicremediesmo.com to learn more about the services provided or schedule a free pharmacist consultation via phone. Once the dispensary is officially open for business, only patients with a valid Missouri Medical Marijuana card and their designated guests may enter the dispensary.

About Organic Remedies
Organic Remedies is a life science organization committed to improving the overall wellness of patients by producing and dispensing affordable quality medical marijuana products while continuing the advancement of medical marijuana therapies through genetics, collaborative research, and superior patient care. Based in Carlisle, Pa., Organic Remedies provides safe, effective medical marijuana therapies to patients in Pennsylvania and Missouri. Organic Remedies delivers a clinical approach for the utilization of medical marijuana that is patient-focused, collaborative and outcomes based.

CONTACT:
Robb Hanrahan
Public Relations
717-329-6264
R.Hanrahan@OrganicRemediesPA.com

Cape G 12cr2

What is Cannabis?

Cannabis is a flowering herb believed to have originated in Central Asia but is now found globally. As early as 2700 BC, there is documented evidence that cannabis was used as a safe and effective therapeutic remedy. Between 1840 and 1900, European and American journals of medicine published more than 100 articles on the therapeutic use of cannabis. In fact, cannabis was part of the American pharmacopoeia until 1942, and is currently available by prescription in the Netherlands, Israel, and Germany.

There are several species of cannabis. Those that contain high levels of the psychoactive chemical THC are commonly known as “marijuana” and used in medicinal marijuana. Those with low levels of THC are harvested commercially worldwide as “hemp” for a variety of products, including rope, paper, and clothing.

There are more than 475 chemical compounds in the cannabis plant, including over 80 medicinal cannabinoids. The two most well-known cannabinoids are THC and CBD.

What is THC? (Tetrahydrocannabinol)

THC is the psychoactive chemical in marijuana. It is the one that gives marijuana its mind-altering reputation. However, it also offers numerous medicinal benefits. THC blocks pain signals from the brain, making it a highly effective pain reliever, especially for nerve-related pain.

THC Molecule Diagram

What is CBD? (Cannabidiol)

The best way to describe CBD is to say it is the opposite of THC. And it is. That is because CBD is an anti-psychoactive chemical. It counteracts the mind-altering properties of THC and provides balance. This is one of the reasons why the different forms of medicinal marijuana are so effective.

CBD is also a highly beneficial chemical. It reduces nausea and suppresses epileptic seizures. Arthritis patients gain measurable relief from its anti-inflammatory properties. CBD slows tumor and cancer cell growth in cancer patients, and it has proven to be effective in treatments for anxiety and depression.

Dosage Forms Available

VAPORIZATION

Medical marijuana can be inhaled via vaporization. There are numerous products to help facilitate this process, including portable vapes, stationary vaporizers, and dabbing instruments.

From a health standpoint, many studies comparing the difference between smoking and vaporizing reveal that there are substantial advantages associated with vaporization which include more efficient cannabinoid extraction and a decreased exposure to toxic elements such as carbon monoxide and tar, which are derived from smoking.

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Vaporizing Dry Herb

Vaporizers designed to heat the cannabis in its raw, bud form are known as dry herb vaporizers. Dry herbs of all sorts have been used for centuries for meditation, relaxation and medicinal purposes. Certain flowers and herbs (including cannabis) can be dried, crushed and then inserted into a vape pen that is dry-herb capable. The vape’s oven chamber will heat up the dry herbs which will release a vapor which can then be inhaled. To get the most out of your vaporization experience, be sure to grind your material using an herb grinder to break your material down to create more surface area for the heat to reach.

TINCTURE

Tinctures are oils derived from the cannabis plant and are typically administered sublingually under the tongue with a dropper. This allows the cannabinoids to immediately enter the bloodstream through the vessel-rich tissues within the sublingual cavity. There are a large number of blood vessels under the tongue and within the mouth which can absorb cannabinoids, so that before you swallow, cannabis can also enter the blood stream.

Sublingual delivery through the oral mucosal membranes in your mouth is an effective way to ingest cannabinoids. This method provides for rapid and effective absorption directly into systemic circulation because of the increased bioavailability of the cannabinoids.

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RSO -RICK SIMPSON OIL

RSO is named after its creator, Rick Simpson, who became well-known for professing his passion for this type of product and its medical efficacy. RSO is produced using a vacuum distillation process, which distills out the solvent and reserves terpenes that would otherwise be lost to open air distillation. RSO is a great option for patients who do not want to vaporize or are uncomfortable swallowing capsules. Used orally, RSO can be absorbed through the mouth sublingually, or swallowed and ingested.

RSO

CAPSULES

Infused capsules are swallowed and absorbed through the gastrointestinal tract for slow onset and long-lasting effects. Capsules are precision dosed with a super-critically extracted marijuana concentrate which has been winterized and infused with coconut butter prior to filling. They are available in multiple formulations, giving patients the ability to select the option that is best for them.

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Edibles

Marijuana edibles can be brownies, cookies , pasta, and more. Any recipe that calls for butter or oil can be readily infused with cannabis. Edible cannabinoids are processed differently than inhaled cannabinoids. When it is ingested, cannabinoids enter the bloodstream through the stomach and liver, which increases potency and delays the onset of effects. Dosing should be carefully considered as an edible experience can be much stronger and last longer than other delivery methods. Effects could take up to three hours to absorb into the body.

Edibles

LOTIONS

Cannabinoids can also be absorbed through the skin. Products designed for this are known as cannabis topicals. The skin has a relatively complex absorption process that involves a chemical’s ability to dissolve in H20. Examples of topical products include lotions, creams, and balms. The topical application of cannabinoids has an onset of action within minutes locally (i.e. creams and balms applied to a joint), with duration of these effects lasting approximately one to two hours.

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CONcENTRATES/EXTRACTS

Cannabis concentrates, commonly referred to as cannabis extracts, are significantly more potent than your standard cannabis buds. Their applications as medicine have proven to be effective for patients suffering from many adverse health conditions. A cannabis concentrate is reminiscent of the cannabis strain it was extracted from; the smell, taste, and effects are simply magnified due to a larger concentration by weight.

Due to these products being a concentrated mix, you have the benefit of only needing a very small amount to get the same effect as you would with larger amounts of a less concentrated mix.

While the number of components released depends on the compounds present and the temperature, none of the toxic biproducts of smoking plant matter is present in the vapor. This means that vapor will have a much higher percentage of desired cannabinoid /terpenoid content when compared to smoke.

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Live Sugar – a shimmery crystalline concentrate made using the fresh-frozen material.

Budder – a smooth and creamy concentrate that resembles peanut butter in consistency.

Wax – a concentrate that easily breaks apart into smaller-sized pieces. Easy to work with using only your hands.

Live Budder – a smooth and creamy concentrate made using the fresh-frozen material.

Shatter – a translucent, glass-like concentrate that ‘shatters’ when tapped on a hard surface.